The College of Education for Pure Sciences, in cooperation with the Center for Development and Continuing Education at the University of Basrah, organized a workshop in the Chemistry Department entitled (Ketoacids selected to form basic building blocks towards the formation of biologically active compounds)
The workshop was presented by the lecturer (Professor Ahmed Majeed Jassim) / Department of Chemistry
The workshop aims to...
Definition of keto acids or keto acids (also called oxo acids or oxo acids) are organic compounds that contain a carboxylic acid group (COOH) and a ketone group (C=O) in several parts. A definition of the importance of ketoacids because they are considered acids of special importance in biology because they participate in the Krebs-citric acid cycle and in glycolysis. Mostly generated by the oxidation state of amino acids, alpha-keto acids such as phenylpyruvic acid are endogenous sources of carbon monoxide (as a gaseous carrier), and pyruvic acid is a widespread intermediate in metabolism. As for oxaloacetic acid, it is a component of the Krebs cycle. Ketoglutarate acids, derived from glutamic acid, participate in cell signaling by acting as a coenzyme usually used in transport reactions.
And clarifying the ways to produce keto acids from an environmental perspective, as keto acids are found in a wide range of pathways that contribute to the metabolism process. In plants (eg hemlock, pitcher plants, and parsley), 5-OXO is converted in enzymatic and non-enzymatic steps to the cyclic class of coniine alkaloids. Also, when the levels of sugar and carbohydrates consumed are low, stored fats and proteins are the main source of energy production. Also, glucogenic amino acids are converted from proteins or glycerol from triglycerides into glucose. Ketogenic amino acids can be converted to produce alpha-keto acids and ketone bodies.
Explaining laboratory methods for the organic synthesis of ketoacids, traditional methods and modern methods
A detailed laboratory study supported by modern sources to prove the role of keto acids as a basic building block for the preparation of many organic derivatives with promising biological activity.
The workshop was attended by Mr. Assistant Dean for Scientific Affairs, Prof. Dr. Abdul Sattar Jaber Ali, Mr. Head of the Chemistry Department, Prof. Dr. Muayyad Yousef Kazem, and a group of department professors and graduate students. This was in the department council hall in the Chemistry Department, and a discussion took place between the lecturer and professors in attendance, and the organizers recommended The workshop calls for the necessity of communicating with graduate students with all the latest scientific achievements within the department and also to find solutions to some of the obstacles they face in scientific research.