The College of Education for Pure Sciences at the University of Basra discussed a master’s thesis on the common life chemo relationship between sex hormones and (vitamin - D, lipid pattern and some enzymes) in pregnant women in Basra Governorate - Iraq
The message presented by the researcher (Edited by Fadel Abbas) included
Pregnancy is a natural physiological process in a pregnant woman, so the body must prepare for it functionally, and the changes that coincide with the requirements of the mother and fetus in order to reach a successful natural birth. Hormones participate in organizing all physiological and chemical activities in pregnant bodies as well as on blood components.
The current study was completed in Basra Hospital for Women and Children in Basra Governorate - Iraq for pregnant and non-pregnant women. The total number of samples was 125 samples divided into 60 samples (for pregnant women) and 65 samples for married women who are not pregnant (control group), and the ages of each of the pregnant women and the control group ranged between (15-41 years).
Our study aimed to evaluate the biochemical relationship between sex hormones and D in pregnant women. Estimation and investigation of the concentration of sex hormones (estrogen, testosterone and progesterone), vitamin D, and lipid pattern, which are triglycerides, total cholesterol level, high-density protein, low-density protein, and low-density protein Very, and some liver enzymes such as (Aspartate transaminase (AST), Alanine aminotransferase (ALT)) and antioxidant enzymes (superoxide dismutase (SOD), Catalase (CAT), Glutathione peroxidase (GPX)). It was found that healthy pregnant women had a significant increase in the concentrations of sex hormones (estrogen and progesterone) and the results of vitamin D showed a significant increase in the concentration of vitamin D and triglycerides ((TG and HDL)) compared with non-pregnant women (P<0.0001)). Also, the results of the study indicated that there were significant differences in the concentrations of (SOD, GPX) and (ALT) in pregnant women when compared with non-pregnant women (P<0.001) and (P<0.05), respectively. There were no significant differences in the concentration of testosterone, total cholesterol, low-density lipoprotein, very low-density lipoproteins, AST and CAT when compared to non-pregnant women. The study showed an increase in the concentrations of sex hormones (estrogen and progesterone), vitamin D concentration, triglycerides, total cholesterol, high-density lipoprotein (HDL) and SOD) according to age and blood type factors. There was also a significant increase in the concentration of low-density protein lipids (P<0.001), according to the blood type factor. The study also showed a significant difference in the concentrations of very low-density lipoprotein, ALT, estrogen, progesterone and vitamin (D) (P<0.05) according to age, blood type, and month of pregnancy. No significant differences were found in the level of enzymes (CAT, SOD, GPX). According to the sex factors of the fetus and the month of pregnancy. It was also noted that there was a significant positive correlation between the concentration of the hormones estrogen and progesterone and the concentration of vitamin D, and there was also a significant positive correlation between the hormones estrogen, progesterone, triglycerides, and low-density protein lipids in pregnant women.