
The College of Education for Pure Sciences in the Department of Chemistry organized a scientific lecture on (preparation, diagnosis, and analytical study of some new Schiff rules, and study of their effectiveness as antibody to MCF-7 human breast cancer).
The lecture presented by the researcher (Mustafa Mohsen Karafa) aims to
Preparing some new single- and dual-link schiff bases.
Diagnosing the prepared compounds and studying their toxicity on human red blood cells. And an analytical study of the rules of the prepared scheff, which includes:
Or study the effect of organic solvents of different polarity on the absorption peaks of the prepared Schiff bases.
Studying the effect of the acid function on the prepared bases, calculating the ionization and protonation constants with different solutions, the acid function, determining the azobasic points and proposing their mechanisms.
And study the effectiveness of the new Schiff bases as antidote to human breast cancer type MCF-7, including the following:
Study of the efficacy of new Schiff bases against human breast cancer cells type
Study of the effect of concentration on the inhibitory activity of breast cancer cells type MCF-7 .
Calculation of the IC50 inhibitory half-concentration of human breast cancer cells type MCF-7 .
Study of the highest effect of the prepared bases on the growth, shape and shape of human breast cancer cells MCF-7 type.